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Jeanne D. | Sport | Nutrition | Wellness on Instagram: "Enzymes convert vitamin D into two active forms: first into calcidiol in the liver, then into calcitriol in the kidneys. These reactions require cofactors — vitamins and minerals that support enzymatic activation: • Magnesium – key cofactor for both conversion stages. • Zinc – supports the activity of liver enzymes. • Vitamin B2 (riboflavin) – participates in redox reactions. • Selenium – essential for antioxidant defense and kidney enzyme
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Vitamin D supports bone health by increasing calcium absorption. At high supplemental doses, that same mechanism can overshoot, raising calcium levels and stressing the kidneys. That’s why testing before heavy supplementing matters. 🦴 Why vitamin D raises calcium Activated vitamin D (calcitriol) increases intestinal absorption of calcium and phosphate. In deficiency, this supports bone mineralization. With high-dose supplementation on top of normal intake, calcium can rise excessively, leading
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