A microbial sensor that helps identify and fight bacterial infections also plays a key role in the embryonic development of blood stem cells, valuable new insight in the effort to create ...

Immunotherapy, which uses programmed immune cells to selectively destroy cancer cells, has transformed cancer treatment. However, cancer cells have developed immune evasion strategies, leading to poor ...

Yale scientists have discovered a family of immune proteins, which they describe as a “massive molecular machine,” that could affect the way our bodies fight infection. Our immune system mobilizes ...

Trillions of microorganisms live in the human gut, collectively forming the gut microbiome. They support important bodily ...

Immune checkpoint inhibitors are cancer therapeutics that have shown remarkable success in extending lives in many cancers, including melanoma, MSI-high cancers, and other cancers. However, these ...

During the recent Covid-19 pandemic, the rate of serious illness and death was jarringly high in older populations. Why? Weakening immune systems — as we age, we become more vulnerable to infections, ...

An estimated 2.8 million people worldwide have multiple sclerosis (MS). This autoimmune condition is the result of the immune system damaging parts of the nerves in the brain and spinal cord, which ...

Gabriel D. Victora's team has turned germinal centers into a living laboratory for one of biology's oldest questions: how ...

Researchers from Japan, discover mitochondrial transfer from cancer cells to immune cells and metabolic reprogramming of the tumor microenvironment as a key immune evasion strategy. Targeting ...