Ischemia reperfusion injury (IRI) is one of the main cause of organ dysfunction after heart attack and solid organ transplantation, and occurs frequently when the new organ comes from a deceased ...
The idea that the gap junction family of proteins, connexins, are tumour suppressors has been widely supported through numerous cancer models. However, the paradigm that connexins and enhanced gap ...
Twenty-week-old male SHR and WKY rats were used in this study. All protocols were approved by the Institutional Animal Care and Use Committee (IACUC) at the Medical College of Shihezi University and ...
In their May 2015 Scientific American article “Cellular Small Talk,”Dale W. Laird, Paul D. Lampe and Ross G. Johnson report on recent discoveries showing that the disruption of cellular structures ...
TNBCs rely on fatty acid oxidization (FAO) to fuel tumor growth by breaking down surrounding adipose tissue through lipolysis. Gap junctions, particularly involving GJB3 and connexin 31 (Cx31), ...
Cells communicate with one another during development, but what are the steps that enable them to transition from local cell-cell communication to a globally synchronized tissue-scale behavior?
Neighboring cells exchange molecular information via channels that directly connect them. Disruption of this signaling system can lead to disorders ranging from hearing loss to heart disease Like ...
A new study by the University of California, Davis, shows how cells work together to avoid a sudden drop in blood sugar. Understanding these feedback loops could improve the lives of people with ...
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