CCN5 reduced cardiac cellular senescence in preclinical models of cardiovascular disease. Learn how this could shape ...

Geroscience examines the underlying biology of aging to delay chronic diseases and extend the healthy years of human life.

New research from the University of Minnesota Medical School has identified fatty acids that selectively induce death in ...

Muscles age differently than you think. Discover the science behind the aging muscle paradox—and how exercise can help you stay strong and biologically young.

Cellular senescence is a process in which the cell cycle becomes permanently arrested, thereby inhibiting cell division, proliferation and growth. Various cellular stresses, such as DNA damage, ...

Aging cells secrete substances known to promote the growth of cancer cells. The development of drugs that can selectively kill these cells or inhibit the secretion of substances is ongoing. The latest ...

Scientists have identified prematurely aged astrocytes in the brains of Alzheimer’s patients, particularly those with the APOE4 risk gene. Their findings suggest that cellular senescence in these ...

Senescence, aging, and age-related diseases represent complex biological phenomena with significant impacts on human health, and metabolism and metabolomics play pivotal roles in understanding their ...

This Collection supports and amplifies research related to SDG 3. This is a joint Collection across npj Aging, Nature Aging, Nature Metabolism, Nature Cell Biology and Scientific Reports. Please see ...

Aging cells secrete substances known to promote the growth of cancer cells. The development of drugs that can selectively kill these cells or inhibit the secretion of substances is ongoing. The latest ...